It marked the first time an attempt was made to calculate the cumulative number of people who had had Covid-19 for much of the pandemic.
The data is compiled by the ONS’s Covid-19 infection survey, which began April 27, 2020, and does not include figures for the initial wave that began in early March.
Professor James Naismith of Oxford University said the figures provided a “valuable piece of data” but warned the number of infected people was “increasing rapidly” towards the end of the survey period.
“In some parts of England today, I would expect the proportion of people who have had Covid-19 to easily exceed 80 per cent,” he added.
Separate estimates have been published for three other UK countries, each covering a different time period depending on when the infection investigation began.
In Wales, 1.7 million people – or 56.0% of the population – are likely to have contracted Covid-19 between 30 June 2020 and 11 February 2022.
In Scotland, 2.7 million people (51.5% of the population) contracted the virus between 22 September 2020 and 11 February this year.
And in Northern Ireland, 1.3 million people, or 72.2% of the population, are estimated to have contracted Covid-19 between 27 July 2020 and 11 February 2022.
All figures are for people in private households and do not include people in hospitals, care homes and other social settings.
The data also shows how each wave of the virus pushes the cumulative number of infected people up.
By the start of the second wave in September 2020, the percentage of the population in the UK who had used Covid-19 since 27 April was still very low, just under 2% of the population.
Once the second wave began, this number increased to 10% by mid-December and 15% by mid-January 2021.
This number then slowed down, reaching 25% in early August and 40% in late November.
When Omicron The wave started last December, the rate of increase is rapid, with rates reaching 50% by the end of December, 60% by mid-January 2022, and 70% by early February.
Professor Naismith said: “We suffered a huge wave with Omicron, now it is slowly settling down.
“The six-month period to February 2022 has seen incidence rates more than double compared with the 20-month period from April 2020 to October 2021.
“Another way of saying this is that the majority of the most vulnerable people in the UK were infected after they were protected from vaccination.
“Thanks to the vaccine, Omicron infections are significantly less severe for the vaccinated individual,” he continued.
The ONS Covid-19 Infection Survey is considered the most reliable measure of the prevalence of coronavirus across the country and the number of people who have been infected at least once.
This is a nationally representative survey that examines a large number of people each month.
The same people are tested again, regardless of whether they have symptoms or not, meaning the survey can identify both infection and reinfection as well as asymptomatic cases.